Local News
Eyewitness Sports
Medical Coverage
Call 12 For Action
Target 12 Investigators
More Details
What's On WPRI
What's On Fox
This Morning Weekend
Experts Online
Online Store
Chopper 12
Station Info

 May 11, 2005
Breast Cancer Drug Bests Tamoxifen at Stopping Relapse
Email to a Friend Printer Friendly Version  

The newer breast cancer drug Arimidex clearly outperforms tamoxifen at preventing the disease from returning, an international study finds.

Arimidex (anastrozole), made by AstraZeneca, appeared to prevent relapse in up to 80 percent of postmenopausal cases, vs. the 50 percent normally credited to tamoxifen, the Associated Press reported Wednesday.

"[Arimidex] is a better drug," said University of Texas researcher Dr. Aman Buzdar, who led the U.S. portion of the five-year study, which involved 2,000 American women and about 7,300 more from 20 other countries. The study, published in the online edition of The Lancet, was funded by AstraZeneca.

Tamoxifen, approved by the U.S. Food and Drug Administration some three decades ago, stifles the tumor-promoting properties of the female hormone estrogen. Arimidex, among a new class of drugs called aromatase inhibitors, prevents estrogen from being made in the first place, the AP reported.

Experts both in and outside the study cautioned that the research hadn't been conducted long enough to determine if Arimidex improved users' overall survival, the wire service reported. Since study participants had very early cancers and had among the best prognoses, it wasn't possible to compare survival statistics among users of the newer drug vs. the older standard. That, the experts said, would take longer than five years.


Copyright � 2004 ScoutNews, LLC. All rights reserved.

Health News | Health Encyclopedia | Quizzes and Tools | Women's Health | Men's Health | Children's Health | Seniors' Health | Diet, Fitness and Self Image | Sex and Relationships

Health Encyclopedia: Depression
Seasonal Affective Disorder
Depression (Bipolar Disorder)
You are not alone...
Depression Related News
Consumer Ads Can Alter Prescribing Patterns
Direct-to-Consumer Ads Alter Prescribing Patterns
Sopranos Psychiatrist Gets Tough on Depression
Implanted Electrodes Combat Depression
Health Tip: For Many, Winter is SAD Time
Light Boxes Help Lift the Winter Blues
Unmarried Same-Sex Couples Lose Health Benefits in Mass.
Breast Cancer Drug Bests Tamoxifen at Stopping Relapse
Caution Urged on Antidepressants and Children
A Troubling Return for Iraq Vets
Send questions and comments about this website to the .
All content © Copyright 2003-2005 WorldNow, WPRI, WNAC and Associated Press. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.