Local News
Eyewitness Sports
Medical Coverage
Call 12 For Action
More Details
What's On WPRI
What's On Fox
This Morning Weekend
2 Minute Test Drive
Experts Online
Online Store
Chopper 12
Station Info

 March 31, 2005
FDA Seizes Depression, Diabetes Drugs
Email to a Friend Printer Friendly Version  

Citing poor manufacturing practices at three GlaxoSmithKline production plants, the U.S. Food and Drug Administration has seized inventories of two prescription drugs to treat depression and type 2 diabetes, the FDA announced Friday.

The seizure by U.S. marshals at plants in Puerto Rico and Tennessee involved the antidepressant Paxil CR (controlled release) and the diabetes medication Avandamet. In a statement on its Web site, the agency said several inspections since 2002 had uncovered poor manufacturing practices that hadn't been corrected.

The firm had recalled some of the affected lots, but its failure to recall all affected products forced the FDA to seek court permission for the drugs' seizure, the agency said.

The FDA said it wasn't aware of any reports of harm to consumers, and recommended that people who currently have supplies of these drugs continue to take them. In the long-term, the agency suggested, patients should speak to their doctor about finding alternatives until the manufacturing deficiencies are fixed.

The FDA said recent inspections found that "Paxil CR tablets could split apart and patients could receive a portion of the tablets that lacks any active ingredient or alternatively a portion that contains active ingredient and does not have the intended controlled-release effect." The immediate release form of Paxil is not affected, the agency said.

Some of the Avandamet tablets, the FDA noted, were found to contain inaccurate amounts of the active ingredient, rosiglitazone.

The FDA acknowledged the possibility of shortages of both medications until the manufacturing problems are corrected.


Copyright � 2005 ScoutNews, LLC. All rights reserved.

Health News | Health Encyclopedia | Quizzes and Tools | Women's Health | Men's Health | Children's Health | Seniors' Health | Diet, Fitness and Self Image | Sex and Relationships

Health Encyclopedia: Children's Health
Pervasive Developmental Disorders
Otitis Externa
Umbilical Cord Blood
Umbilical Hernia In Infants
Precocious Puberty
Reye's Syndrome
Attention Deficit/Hyperactivity Disorder
Learning Disabilities
Children's Health News
Health Tip: Child Safety Seats
Petting Zoo Connection Probed in Child Kidney Cases
Health Tip: Backpack Injuries
McGwire Refuses to Offer Names to House Steroid Committee
No Tanning Beds for Kids Under 18, Experts Warn
Health Tip: Bird Flu Is Nothing To Sneeze At
Health Tip: Baby Bottle Tooth Decay
Health Tip: Are You an Alcoholic?
Pope to Return to Vatican for Holy Week
Experts Suggest Euthanasia for Severely Disabled Newborns
Send questions and comments about this website to the .
All content © Copyright 2003-2005 WorldNow, WPRI, WNAC and Associated Press. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.